HCID 19800636, compound → HCID 19800643, compound

Participants

Reaction Steps

A solution of diethyl-4-hydroxy-5-nitrophthalate (16.0 g, 56.7 mmol) in ethanol is treated with 10% palladium on carbon (1.6 g) and shaken overnight at room temperature on a Parr hydrogenator. After evacuation of hydrogen, the reaction mixture is filtered through diatomaceous earth. The filtrate is concentrated in vacuo to afford the title product as a yellow oil, 14.3 g (100%) identified by NMR spectral analysis.

Provenance & Evidence