Dimethyl Sulfoxide → HCID 19801147, compound

Participants

Reaction Steps

Dimethyl sulphoxide (293 mg) in dry dichloromethane (3 ml) was added to oxalyl chloride (162 mg) in dichloromethane (14 ml) at -60° C. After 10 minutes the above alcohol (0.73 g) in dichloromethane (3 ml) was added and the mixture kept at -60° C. for 1 hour. Triethylamine (1.01 ml) was added and the whole allowed to reach 0° C. gradually. Conventional work-up gave (Z)-2-fluoro-9-(bistrifluoromethylbenzyloxy)non-2-ene-1-al.

Provenance & Evidence