Water → 1-Indanol

Participants

Reaction Steps

1.28 g of 1-indanone in 13 ml of anhydrous ethanol is cooled to +5° C. 0.23 g of sodium borohydride at 95% is added in small fractions, with agitation at +10° C. for one hour. 0.23 g of sodium borohydride at 95% is again added at +5° C., with agitation at 20° C. for one hour 30 minutes. The reaction mixture is poured into 60 ml of water containing sodium chloride and is extracted with isopropyl ether; the extracts are dried and brought to dryness under reduced pressure and the residue is chromatographed on silica in a hexane-ethyl acetate mixture (6-4). 1.15 g of expected product is isolated.

Provenance & Evidence