2-Bromobenzyl bromide → HCID 86746497, compound

HRID 1646650Notes

Reaction equation

HRID 1646650 reaction equation
[O:1]1[CH:3]([CH2:4][CH:5]=[C:6]([CH3:8])[CH3:7])[C:2]1([CH:10]1[CH:15]([O:16][CH3:17])[CH:14]([OH:18])[CH2:13][CH2:12][C:11]1([CH2:20][S:21][CH3:22])[OH:19])[CH3:9].[Br:23][C:24]1[CH:31]=[CH:30][CH:29]=[CH:28][C:25]=1[CH2:26]Br>>[Br-:23].[Br:23][C:24]1[CH:31]=[CH:30][CH:29]=[CH:28][C:25]=1[CH2:26][CH2:22][SH+:21][CH2:20][C:11]1([OH:19])[CH2:12][CH2:13][CH:14]([OH:18])[CH:15]([O:16][CH3:17])[CH:10]1[C:2]1([CH3:9])[O:1][CH:3]1[CH2:4][CH:5]=[C:6]([CH3:7])[CH3:8]

Participants

3

Reactant 2

HCID 769652-Bromobenzyl bromideHCID 19801008HCID 19801008, compound

Product 1

HCID 86746497HCID 86746497, compoundYield 8.3%

Procedure

As in Example 54, 2-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-3-methoxy-1-methylthiomethyl-1,4-cyclohexanediol (200 mg) was allowed to react with 2-bromobenzyl bromide (1.51 g) to give 1-(2-bromobenzyl)methylsulfoniomethyl-2-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-3-methoxy-1,4-cyclohexanediol bromide (29 mg: yield 8%) as colorless powder.

Sources & evidence

ORD record
ord-3c1adfe6e5f5415c9e4dee903ad09fba
Source dataset
uspto-grants-1993_01
Patent number
US05180735

Reaction notes

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