huagongshe.com
HRID1646782

反应详情

EQUATION

反应方程式

HRID 1646782 的结构方程式

REACTANTS

反应物

3
结构：CCCCCCCCCCCC(=O)Cl
HCID8166

Dodecanoyl chloride

C12H23ClO

结构：CC1C(c2ccccc2)NC(c2ccccc2)C(C)C1O
HCID338206

3,5-dimethyl-2,6-diphenylpiperidin-4-ol

C19H23NO

结构：[Li]CCCC
HCID178418339

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCCCCC(=O)OC1C(C)C(c2ccccc2)NC(c2ccccc2)C1C
HCID53685275

未命名化合物

收率 74.4%

PROCEDURE

实验过程

The general procedure of Example 1 is repeated using 28.1 g (0.10 mol) of 2,6-diphenyl-3,5-dimethyl-4-hydroxypiperidine, 40 mL (0.10 mol) of n-butyllithium (2.5M in hexanes) and 21.8 g (0.10 mol) of lauroyl chloride. 34.5 g (74% yield) of the title compound is isolated after purification by LC (silica gel, ethyl acetate/hexane): mp 74°-76° C.