Benzenesulfonyl chloride → HCID 19800028, compound

HRID 1646895Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][C:4]([O:6][CH3:7])=[O:5].[C:8]1([S:14](Cl)(=[O:16])=[O:15])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[CH3:7][O:6][C:4](=[O:5])[CH2:3][CH2:2][NH:1][S:14]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)(=[O:16])=[O:15]

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 192794Methyl beta-alanate

Product 1

HCID 19800028HCID 19800028, compound

Procedure

N-(phenylsulfonyl)-β-alanine methyl ester (23) was prepared from methyl β-alaninate and phenylsulfonyl chloride on a 32 mmol scale in the manner described above in Example 13 to yield 6.76 g (86%) of product. Analysis calculated for C10H13NO4S (M.W. 243.28): C, 49.37; H, 5.39; N, 5.76; S, 13.18. Found: C, 49.06; H, 5.46; N, 5.78; S, 12.95.

Sources & evidence

ORD record: ord-8c263d3312b4464bb06efa38133d84bb
Source dataset: uspto-grants-1993_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05182272

Reaction notes

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