1-Bromo-3-chloropropane → HCID 19800124, compound

Participants

Reaction Steps

Using the procedure of Step E of Example 1, 6.7 g of 2-[1-(1H-indol-4-yl)-ethenyl]-phenol of Step A of Example 22, 70 ml of acetone, 4 g of potassium carbonate and 11.5 ml of 1-chloro-3-bromo-propane were heated for 20 hours at reflux and after Chromatography and crystallization from petroleum ether (Eb=40-70° C.), 7.05 g of the desired product melting at 70 to 72° C. were obtained.

Provenance & Evidence