Chlorotrimethylsilane → HCID 178504308, compound

Participants

Reaction Steps

A solution of 7.8 g of p-bromophenol in 15 ml of tetrahydrofuran and then 5.75 ml of trimethylsilyl chloride were added to 50 ml of a solution of 0.9M of isopropyl magnesium chloride per liter of tetrahydrofuran and the resulting solution was poured over 1.2 g of magnesium turnings. A little 1,2-dibromoethane and then 2 ml of hexamethylphosphortriamide were added to the mixture which was refluxed for 21/2 hours to obtain a solution of 4-trimethylsilyloxy-phenyl magnesium bromide.

Provenance & Evidence