HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-butoxycarbonyl)-L-aspartic acid → N,N'-[[(S)-(1-t-butoxyformamido)ethylene]dicarbonyl]di-beta-alanine dibenzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-butoxycarbonyl)-L-aspartic acid | HCID 99718 | — |
| Reactant | Benzyl 3-aminopropanoate | HCID 1116164 | — |
| Product | N,N'-[[(S)-(1-t-butoxyformamido)ethylene]dicarbonyl]di-beta-alanine dibenzyl ester | HCID 22849523 | — |
Reaction Steps
N-(t-butoxycarbonyl)-L-aspartic acid is coupled with two equivalents of β-alanine benzyl ester to give N,N'-[[(S)-(1-t-butoxyformamido)ethylene]dicarbonyl]di-β-alanine dibenzyl ester, m.p. 109°-110° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05430024 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-fddf1ab4d3d94aef8575dc50d7ecedcd |
| Source note | uspto-grants-1995_07 |