HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 129061122, compound → N-Phenylacetyl-L-leucine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 129061122 | HCID 129061122 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-Phenylacetyl-L-leucine | HCID 11983894 | 74.9% |
Reaction Steps
A solution of N-phenylacetyl-L-Leu-OBzl (14 g) in methanol (140 ml) was hydrogenated over 10% palladium on carbon (1.4 g) at 3 atmospheric pressure of hydrogen for 2 hours. After removal of the catalyst by filtration, the filtrate was concentrated in vacuo. The residue was triturated with diisopropyl ether to give N-phenylacetyl-L-Leu-OH (7.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05430022 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-c5e8482572cf4c98a0464ab7a7bbc715 |
| Source note | uspto-grants-1995_07 |