HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(3-Oxo-3-phenyl-1-propenyl)-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetophenone | HCID 7410 | — |
| Reactant | 3-Carboxybenzaldehyde | HCID 12077 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | 3-(3-Oxo-3-phenyl-1-propenyl)-benzoic acid | HCID 54028671 | 84.5% |
Reaction Steps
A mixture of 3-formylbenzoic acid (2 g, 13.32 mmol), acetophenone (1.6 g, 13.32 mmol), and sodium hydroxide (1.06 g, 26.64 mmol) is stirred 18 hours in ethanol-water (175 mL, 1:1) and then acidified with concentrated hydrochloric acid. The resulting solid is collected by filtration and dried to provide 2.84 g of the title compound; mp 198°-201° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05430047 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-d25eeba8162d47098888e116c3e85b95 |
| Source note | uspto-grants-1995_07 |