4-Chlorobenzylamine → HCID 19926902, compound

HRID 1647281Notes

Reaction equation

[C:1]([C:4]1[C:5](=[O:24])[NH:6][C:7]2[C:12]([C:13]=1C)=[C:11]([N+:15]([O-:17])=[O:16])[C:10](OS(O)(=O)=O)=[CH:9][C:8]=2[Cl:23])(=[O:3])[CH3:2].[Cl:25][C:26]1[CH:33]=[CH:32][C:29]([CH2:30][NH2:31])=[CH:28][CH:27]=1>>[C:1]([C:4]1[C:5](=[O:24])[NH:6][C:7]2[C:12]([C:13]=1[NH:31][CH2:30][C:29]1[CH:32]=[CH:33][C:26]([Cl:25])=[CH:27][CH:28]=1)=[C:11]([N+:15]([O-:17])=[O:16])[CH:10]=[CH:9][C:8]=2[Cl:23])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 660364-Chlorobenzylamine

HCID 86748765HCID 86748765, compound

Product 1

HCID 19926902HCID 19926902, compoundYield 57.1%

Procedure

3-Acetyl-8-chloro-4-methylsulfoxy-5-nitro-2-quinolinone (3.28g, 0.01 mol ) and p-chlorobenzylamine (1.42g, 0.01 mol) were used, but the reaction was carried out as the above process of example 37 to obtain the desired product (2.32g, yield: 57%).

Sources & evidence

ORD record: ord-e1fcda23326447ed87f7b67a30d2e769
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430153

Reaction notes

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