2-Phenylpropylamine → HCID 19926877, compound

HRID 1647285Notes

Reaction equation

[C:1]([C:4]1[C:5](=[O:26])[NH:6][C:7]2[C:12]([C:13]=1C)=[C:11](OS(O)(=O)=O)[CH:10]=[CH:9][C:8]=2[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)(=[O:3])[CH3:2].[CH3:27][CH:28]([C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[CH2:29][NH2:30]>>[C:1]([C:4]1[C:5](=[O:26])[NH:6][C:7]2[C:12]([C:13]=1[NH:30][CH2:29][CH:28]([CH3:27])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)=[CH:11][CH:10]=[CH:9][C:8]=2[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 113982-Phenylpropylamine

HCID 86748767HCID 86748767, compound

Product 1

HCID 19926877HCID 19926877, compoundYield 83%

Procedure

3-Acetyl-4-methylsulfoxy-8-phenyl-2-quinolinone (3.25g, 0.01 mol) and β-methylphenethylamine (1.35g, 0.01 mol) were used, but the reaction was carried out as the above process of example 37 to obtain the desired product (3.29g, yield: 83%).

Sources & evidence

ORD record: ord-db93a700f9d7441a8a5cdf4351589ef6
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430153

Reaction notes

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