Isobutylamine → HCID 19926922, compound

HRID 1647288Notes

Reaction equation

[C:1]([C:4]1[C:5](=[O:26])[NH:6][C:7]2[C:12]([C:13]=1C)=[C:11]([C:15]([F:18])([F:17])[F:16])[C:10](OS(O)(=O)=O)=[CH:9][C:8]=2[O:24][CH3:25])(=[O:3])[CH3:2].[CH2:27]([NH2:31])[CH:28]([CH3:30])[CH3:29]>>[C:1]([C:4]1[C:5](=[O:26])[NH:6][C:7]2[C:12]([C:13]=1[NH:31][CH2:27][CH:28]([CH3:30])[CH3:29])=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=[CH:9][C:8]=2[O:24][CH3:25])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 6558Isobutylamine

HCID 131719034HCID 131719034, compound

Product 1

HCID 19926922HCID 19926922, compoundYield 69%

Procedure

3-Acetyl-5- trifluoromehyl-8-methoxy-4-methylsulfoxy-2-quinolinone (3.4 7g, 0.01 mol) and isobutylamine (0.73g, 0.01 mol) were used, but the reaction was carried out as the above process of example 37 to obtain the desired product (2.46g, yield: 69%).

Sources & evidence

ORD record: ord-18fa1284076e4c9594b6049b89513d93
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430153

Reaction notes

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