HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methyl-N-(3,4,5-trimethoxybenzyl)aniline → 4-Methoxy-N-(3,4,5-trimethoxybenzyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methyl-N-(3,4,5-trimethoxybenzyl)aniline | HCID 373798 | — |
| Reactant | 151221-92-0 | HCID 373989 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Product | 4-Methoxy-N-(3,4,5-trimethoxybenzyl)aniline | HCID 364716 | 93.5% |
Reaction Steps
From 108c (10.8 g, 35.8 mmol) and NaBH4 (6.8 g, 179 mmol), a similar procedure as described for 109a gave 109c (10.1 g, 93.5%) as pale purple crystals. 1H NMR (200 MHz, CDCl3) δ6.79 (d, J=8 Hz, 2H), 6.62 (d, J=8 Hz, 2H), 6.61 (s, 2H), 4.21 (s, 2H), 3.84 (s, 9H), 3.74 (s, 3H). CIMS (isobutane) m/e 304 (MH+, 20).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05430062 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-be825ab54b76401ab0168a5c56006e1c |
| Source note | uspto-grants-1995_07 |