HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanamine → HCID 67781312, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanamine | HCID 31018 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate | HCID 151348 | — |
| Reactant | tert-Butoxycarbonyl-L-isoleucine | HCID 2724762 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67781312 | HCID 67781312 | 70.7% |
Reaction Steps
The title compound is prepared by the procedure of Example 1, using 1.0 g of 3-(aminomethyl)pyridine, 2.33 g of N-(tert-butoxycarbonyl)-L-isoleucine, 6.95 g of BOP, 11.95 g of Hunig's base and 15 ml of methylene chloride to give 2.1 g of the desired product after chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05430150 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-c582ab9f799348f0850a32cc62bcd28d |
| Source note | uspto-grants-1995_07 |