Chlorotrimethylsilane → HCID 1549944, compound

HRID 1647342Notes

Reaction equation

HRID 1647342 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=O)[CH2:3][CH:4]([CH3:6])[CH3:5].[NH2:10][C@H:11]([C:19]([OH:21])=[O:20])[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH3:22][Si](Cl)(C)C>CO>[CH3:22][O:20][C:19](=[O:21])[C@H:11]([CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[NH:10][C:7](=[O:9])[C@H:2]([CH2:3][CH:4]([CH3:6])[CH3:5])[NH2:1]

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 18643433HCID 18643433, compound

Product 1

HCID 1549944HCID 1549944, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound is prepared by the procedure of Example 7 using 0.50 g of L-leucine-L-phenylalanine, 10 ml of methyl alcohol and 0.536 ml of trimethylsilyl chloride to give 0.53 g of the desired product.

Sources & evidence

ORD record
ord-3007c05c673d4d769a645e78cc17668d
Source dataset
uspto-grants-1995_07
Patent number
US05430150

Reaction notes

Loading…