Chlorotrimethylsilane → HCID 11129623, compound

HRID 1647343Notes

Reaction equation

HRID 1647343 reaction equation
[NH2:1][C@H:2]([C:6]([OH:8])=O)[CH:3]([CH3:5])[CH3:4].[NH2:9][C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[CH3:21][Si](Cl)(C)C>CO>[CH3:21][O:19][C:18](=[O:20])[C@H:10]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[NH:9][C:6](=[O:8])[C@H:2]([CH:3]([CH3:5])[CH3:4])[NH2:1]

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 22838601HCID 22838601, compound

Product 1

HCID 11129623HCID 11129623, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound is prepared by the procedure of Example 7 using 0.50 g of L-valine-L-phenylalanine, 10 ml of methyl alcohol and 0.564 ml of trimethylsilyl chloride to give 0.57 g of the desired product.

Sources & evidence

ORD record
ord-2e267db365a043ceae9354055fc27d9c
Source dataset
uspto-grants-1995_07
Patent number
US05430150

Reaction notes

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