Chlorotrimethylsilane → L-valyl L-valine methyl ester

HRID 1647344Notes

Reaction equation

HRID 1647344 reaction equation
[NH2:1][C@H:2]([C:6]([OH:8])=[O:7])[CH:3]([CH3:5])[CH3:4].[NH2:9][C@H:10]([C:14]([OH:16])=O)[CH:11]([CH3:13])[CH3:12].[CH3:17][Si](Cl)(C)C>CO>[CH3:17][O:7][C:6](=[O:8])[C@H:2]([CH:3]([CH3:5])[CH3:4])[NH:1][C:14](=[O:16])[C@H:10]([CH:11]([CH3:13])[CH3:12])[NH2:9]

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 86748770Valine v

Product 1

HCID 12944632L-valyl L-valine methyl ester

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound is prepared by the procedure of Example 7 using 0.50 g of L-valine-L-valine, 10 ml of methyl alcohol and 0.689 ml of trimethylsilyl chloride to give 0,657 g of the desired product.

Sources & evidence

ORD record
ord-bf6d79751c054b4f94ecd9be0d73a841
Source dataset
uspto-grants-1995_07
Patent number
US05430150

Reaction notes

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