3'-Chloropropiophenone → HCID 19922822, compound

Participants

Reaction Steps

In another approach illustrated in FIG. 21 the inventors performed a double Skraup reaction between 4-nitro-o-phenylenediamine 60 and two molecules of 3'-chloropropiophenone 61 to afford in ca. 15% yield 4,7-diphenyl-5-nitro-1,10-phenanthroline 62. Specifically, 4-Nitro-o-phenylenediamine 60 was reacted with β-chloropropiophenone 61 under the Skraup reaction conditions to afford in 15% compound 62, which was analyzed and found to have the following physical characteristics:

Provenance & Evidence