Hydrochloric Acid → HCID 19925665, compound

Participants

Reaction Conditions

Reaction Steps

Diethylene glycol (10 ml) and 285 mg of hydrazine monohydrate were added to 5-tert-butyl-2-(4-carboxyphenoxyacetyl)benzofuran (1 g) obtained in Example 14 and the mixture was stirred at 90° C. for 40 minutes. Potassium hydroxide (398 mg) was added to the mixture and then heated at 120° C. for 2 hours with stirring and further heated at 180°-190° C. for 3 hours. The reaction mixture was poured into aqueous solution of hydrochloric acid and the crystals separated out therefrom were filtered to give 0.86 g of crystals.

Provenance & Evidence