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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1647614Generated: November 2, 2026

Imidazo(1,2-a)pyridine → HCID 19925050, compound

https://huagongshe.com/reaction/1647614

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazo(1,2-a)pyridineHCID 78960—
ReactantN-[3-(Bromomethyl)phenyl]-4-(tetradecyloxy)-benzeneacetamideHCID 10052253—
SolventAcetonitrileHCID 6342—
ProductHCID 19925050HCID 1992505081.4%

Reaction Steps

A mixture of 1.5 g of N-[3-(bromomethyl)phenyl]-4-(tetradecyloxy)benzeneacetamide and 1.03 g of imidazo[1,2-a]pyridine in 25 ml of acetonitrile is refluxed under argon for 3.5 hours. The solvent is evaporated and the residue stirred with ether and collected by centrifugation. The solid is washed several times with ether and vacuum dried to give 1.5 g of the desired product as a white powder, m.p. 133°-135° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05432189
Source datasetuspto-grants-1995_07
ORD IDord-a07190ad0b8842a0a34ee0557600b8e4
Source noteuspto-grants-1995_07