4-(3-Chloropropyl)morpholine → HCID 19921075, compound

HRID 1647687Notes

Reaction equation

HRID 1647687 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:12]2[CH:17]([CH2:18][CH3:19])[S:16][C:15](=[O:20])[NH:14][N:13]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH2:10][F:11].Cl[CH2:22][CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1>>[O:28]1[CH2:29][CH2:30][N:25]([CH2:24][CH2:23][CH2:22][N:14]2[N:13]=[C:12]([C:5]3[CH:6]=[CH:7][C:8]([O:9][CH2:10][F:11])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:17]([CH2:18][CH3:19])[S:16][C:15]2=[O:20])[CH2:26][CH2:27]1

Participants

3

Reactant 2

HCID 958344-(3-Chloropropyl)morpholineHCID 19358044HCID 19358044, compound

Product 1

HCID 19921075HCID 19921075, compound

Procedure

In analogy to Example 1, by reacting 5-(3-methoxy-4-fluoromethoxyphenyl)-6-ethyl-3,6-dihydro-1,3,4thiadiazin-2-one with 1-chloro-3-morpholinopropane, 3-morpholinopropyl-5-(3-methoxy-4-fluoromethoxyphenyl)-6-ethyl-3,6-dihydro-1,3,4-thiadiazin-2-one is obtained.

Sources & evidence

ORD record
ord-a7993afcf5b24410893bbbebc61b7139
Source dataset
uspto-grants-1995_07
Patent number
US05434149

Reaction notes

Loading…