Quinoline, 3-bromo-4-nitro-, 1-oxide → HCID 10641049, compound

HRID 1647724Notes

Reaction equation

HRID 1647724 reaction equation
Br[C:2]1[CH:3]=[N+:4]([O-:15])[C:5]2[C:10]([C:11]=1[N+:12]([O-:14])=[O:13])=[CH:9][CH:8]=[CH:7][CH:6]=2.[N:16]12[CH2:23][CH2:22][CH2:21][C:20]1([CH2:24][CH2:25][NH2:26])[CH2:19][CH2:18][CH2:17]2>>[N:16]12[CH2:23][CH2:22][CH2:21][C:20]1([CH2:24][CH2:25][NH:26][C:2]1[CH:3]=[N+:4]([O-:15])[C:5]3[C:10]([C:11]=1[N+:12]([O-:14])=[O:13])=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:19][CH2:18][CH2:17]2

Participants

3

Reactant 2

HCID 84235Quinoline, 3-bromo-4-nitro-, 1-oxideHCID 107969772-(Hexahydro-1H-pyrrolizin-7a-yl)ethanamine

Product 1

HCID 10641049HCID 10641049, compoundYield 87.4%

Procedure

3-Bromo-4-nitroquinoline 1-oxide and 2-(1-azabicyclo[3.3.0]octan-5-yl)ethylamine were reacted in the same manner as in Example 1 to obtain the titled compound in a yield of 87.4%.

Sources & evidence

ORD record
ord-4d8f6900ec2c44b2971414ff1a4e2823
Source dataset
uspto-grants-1995_07
Patent number
US05434165

Reaction notes

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