(Hexahydro-1H-pyrrolizin-7A-YL)methanamine → HCID 10852527, compound

HRID 1647729Notes

Reaction equation

HRID 1647729 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[N:15]12[CH2:22][CH2:21][CH2:20][C:19]1([CH2:23][NH2:24])[CH2:18][CH2:17][CH2:16]2>>[N:15]12[CH2:22][CH2:21][CH2:20][C:19]1([CH2:23][NH:24][C:2]1[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])[CH2:18][CH2:17][CH2:16]2

Participants

3

Reactant 2

HCID 10654304(Hexahydro-1H-pyrrolizin-7A-YL)methanamineHCID 122284651-Chloro-2-nitronaphthalene

Product 1

HCID 10852527HCID 10852527, compoundYield 84.1%

Procedure

1-Chloro-2-nitronaphthalene and (1-azabicyclo[3.3.0]octan-5-yl)methylamine were reacted in the same manner as in Example 1 to obtain the titled compound in a yield of 84.1%.

Sources & evidence

ORD record
ord-8c924c06c56b4f8c8d7651c0f28c43ee
Source dataset
uspto-grants-1995_07
Patent number
US05434165

Reaction notes

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