Methyl cyclohexanecarboxylate → Cyclohexanecarbohydrazide

Participants

Reaction Steps

28 Grams of methyl cyclohexylcarboxylate and 15 g of 85%--NH2NH2.H2O were dissolved in 50 ml of isopropyl alcohol, and the solution was refluxed by heating for 10 hours. The reaction mixture was concentrated, and the crystals precipitated by adding water were collected by filtration, then the crystals were washed with water, then recrystallized from water to yield 20 g of cyclohexane-carbohydrazide in the form of colorless needle-like crystals. Melting point: 155.5°-156.5° C.

Provenance & Evidence