Ethylamine → HCID 67622004, compound

HRID 1647844Notes

Reaction equation

HRID 1647844 reaction equation
[O:1]1[CH2:5][CH2:4][CH:3]([CH2:6][N:7]([C:11](SC)=[CH:12][N+:13]([O-:15])=[O:14])[CH2:8][CH2:9][CH3:10])[CH2:2]1.[CH2:18]([NH2:20])[CH3:19]>>[O:1]1[CH2:5][CH2:4][CH:3]([CH2:6][N:7]([C:11]([NH:20][CH2:18][CH3:19])=[CH:12][N+:13]([O-:15])=[O:14])[CH2:8][CH2:9][CH3:10])[CH2:2]1

Participants

3

Reactant 2

HCID 6341EthylamineHCID 54474509HCID 54474509, compound

Product 1

HCID 67622004HCID 67622004, compound

Procedure

A mixture comprising 0.25 g of 1-[N-{(tetrahydro-3-furanyl)methyl}-N-propylamino]-1-methylthio-2-nitroethylene and 1 ml of 70% aqueous ethylamine solution was stirred for an hour at room temperature. After concentration of the mixture under a reduced pressure, the reaction fluid was purified by silica gel column chromatography (eluent: ethyl acetate/methanol=7/1) to obtain 0.25 g of 1-[N-{(tetrahydro-3-furanyl)methyl}-N-propylamino]-1-ethylamino-2-nitroethylene.

Workup

  1. customAfter concentration of the mixture under a reduced pressure, the reaction fluid was purified by silica gel column chromatography (eluent: ethyl acetate/methanol=7/1)

Sources & evidence

ORD record
ord-09673be2118f4e59a77ab5ff67a8965e
Source dataset
uspto-grants-1995_07
Patent number
US05434181

Reaction notes

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