HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 8-bromooctanoate → (E)-8-[2-(3-Methoxy-3-oxo-1-propenyl)-3-(6-hydroxy-1-hexynyl)phenoxy]octanoic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 8-bromooctanoate | HCID 11107373 | — |
| Reactant | (E)-3-[2-Hydroxy-6-(6-hydroxy-1-hexynyl)phenyl]-2-propenoic Acid Methyl Ester | HCID 67780365 | — |
| Product | (E)-8-[2-(3-Methoxy-3-oxo-1-propenyl)-3-(6-hydroxy-1-hexynyl)phenoxy]octanoic Acid Methyl Ester | HCID 67780421 | 67% |
Reaction Steps
Using the procedure of example 122, (E)-3-[2-hydroxy-6-(6-hydroxy-1-hexynyl)phenyl]-2-propenoic acid methyl ester (example 176) was alkylated with methyl 8-bromooctanoate giving the title compound, in 67% yield, as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05434186 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-9bcb02e69ca5432ba24b8b1c5ca68640 |
| Source note | uspto-grants-1995_07 |