Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1648115Generated: October 30, 2026

Sodium Hydroxide → 2-[(5-Carboxypentyl)oxy]-6-[6-[(3,4-dihydro-4-oxo-8-propyl-2H-1-benzopyran-7-yl)oxy]hexyl]benzenepropanoic Acid Disodium Salt

https://huagongshe.com/reaction/1648115

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant6-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroman-7-yloxy)-hexyl]-phenoxy}-hexanoic acidHCID 9850974—
SolventWaterHCID 962—
Product2-[(5-Carboxypentyl)oxy]-6-[6-[(3,4-dihydro-4-oxo-8-propyl-2H-1-benzopyran-7-yl)oxy]hexyl]benzenepropanoic Acid Disodium SaltHCID 131719049—

Reaction Steps

The dicarboxylic acid from example 157 (10 mmol) was neutralized with 20 mL (20 mmol) of 1N aqueous sodium hydroxide. The resulting mixture was diluted with more water and the solution was freeze-dried giving the title salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05434186
Source datasetuspto-grants-1995_07
ORD IDord-326eec8966b646e68891c59a23ddf1f6
Source noteuspto-grants-1995_07