HCID 54407228, compound → HCID 22854679, compound

Participants

Reaction Steps

N-(N-Acetyl-Tyrosinyl-Valinyl-Alaninyl)-3-amino-4-hydroxy-7-phenyl heptanoic acid t-butyl ester (166 mg, 0.0991 mmol), was dissolved in CH2Cl2 (5 mL) and PDC (56 mg, 0.149 mmoL), was added. The resulting mixture was stirred at rt for 6h. The mixture was filtered through Celite and the solvent was concentrated in vacuo. The residue was chromatographed over silica (95:5, CH2Cl2 :MeOH) to provide the ketone (28 mg) and S.M (33 mg).

Provenance & Evidence