Hydrochloric Acid → HCID 22854679, compound

Participants

Reaction Steps

N-(N-AcetylTyrosinyl-Valinyl-Alaninyl)-3-amino-4-oxo-7-phenyl heptanoic acid t-butyl ester (12 mg) was stirred with MeOH (0.5 mL), water(0.2 mL), and 2N NaOH (0.1 mL) overnight. The mixture was acidified with 2N HCl and was extracted with EtOAc (3×5 mL). The solvent was evaporated and the product was recrystilized from acetone/hexane to provide the title compound (8 mg).

Provenance & Evidence