Sodium Hydroxide → 5H-Indeno(1,2-b)pyridin-5-one

HRID 1648154Notes

Reaction equation

HRID 1648154 reaction equation
[N:1]1[C:14]2[C:5](=C3[C:11](=[CH:12][CH:13]=2)[CH:10]=[CH:9][C:8](=O)[C:7]3=[O:16])[CH:4]=[CH:3][CH:2]=1.[OH-].[Na+]>>[CH:4]1[C:5]2[C:7](=[O:16])[C:8]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[C:14]=2[N:1]=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 199224561-Azaphenanthrene-5,6-dione

Product 1

HCID 774895H-Indeno(1,2-b)pyridin-5-oneYield 53.5%

Procedure

Following the procedure described in Example 608, Part B, 8.2 g (0.04 mole) of 1-azaphenanthren-5,6-dione and 165 ml of 10% sodium hydroxide were heated in a bath at 80°-90° for 3 hours. Identical workup yielded 3.88 g, m.p. 140°-142° of pure 4-azafluoren-9-one.

Workup

  1. temperaturewere heated in a bath at 80°-90° for 3 hours

Sources & evidence

ORD record
ord-3b4756b041194891a25bef5fa52d1175
Source dataset
uspto-grants-1995_07
Patent number
US05434264

Reaction notes

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