HuagongsheHuagongshe Chemistry Print Report · For research reference only
t-Butyl (8-amino-1,2,3,4-tetrahydro-3-quinolyl)carbamate → 5-((Phenylmethyl)methylamino)-5,6-dihydro-4H-imidazo(4,5,1-ij)quinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | t-Butyl (8-amino-1,2,3,4-tetrahydro-3-quinolyl)carbamate | HCID 19108500 | — |
| Reactant | Diethyl ether methanol | HCID 21864698 | — |
| Product | 5-((Phenylmethyl)methylamino)-5,6-dihydro-4H-imidazo(4,5,1-ij)quinolin-2(1H)-one | HCID 19919484 | — |
Reaction Steps
This compound was prepared by following the procedure of Example 44 part B, but substituting 1,2,3,4-tetrahydro-N3 -methyl-N3 -(phenylmethyl)quinoline-3,8-diamine for t-butyl (8-amino-1,2,3,4-tetrahydro-3-quinolyl)carbamate. The bulk of the product was converted to the hydrochloride salt, mp 145°-149° C. from methanol/ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05436240 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-46b35582400e4af981ef697cf605d7e3 |
| Source note | uspto-grants-1995_07 |