Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl (dimethylamino)propanedioate → 5,6-Dihydro-N,N-dimethyl-4H-pyrrolo(3,2,1ij)quinolin-5-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl (dimethylamino)propanedioate | HCID 2801725 | — |
| 반응물 | tert-Butyl 4-(bromomethyl)-1H-benzo[d]imidazole-1-carboxylate | HCID 15744964 | — |
| 용매 | Ether tetrahydrofuran | HCID 21868444 | — |
| 생성물 | 5,6-Dihydro-N,N-dimethyl-4H-pyrrolo(3,2,1ij)quinolin-5-amine | HCID 11469718 | — |
반응 단계
This compound was prepared by following the procedure of Example 18, but substituting methyl 7-(bromomethyl)-1H-indole-1-carboxylate for t-butyl 4-(bromomethyl) -1 H-benzimidazole-1-carboxylate and diethyl (dimethylamino)malonate for diethyl (dipropylamino) malonate. The bulk of the product was converted to the maleate salt, mp 114°-115° C. from THF/ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05436240 |
| 출처 데이터셋 | uspto-grants-1995_07 |
| ORD ID | ord-919b76de78dd4f969d27b23258461909 |
| 출처 메모 | uspto-grants-1995_07 |