HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(1H-indol-3-yl)-2-methylpropan-2-amine → [2-(1H-indol-3-yl)-1,1-dimethylethyl][2-(2-ethyloxy-phenoxy)ethyl]amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(1H-indol-3-yl)-2-methylpropan-2-amine | HCID 9353 | — |
| Reactant | 5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine | HCID 13260 | — |
| Reactant | 2-(2-Ethoxyphenoxy)ethyl methanesulfonate | HCID 15289994 | — |
| Product | [2-(1H-indol-3-yl)-1,1-dimethylethyl][2-(2-ethyloxy-phenoxy)ethyl]amine hydrochloride | HCID 19919947 | — |
Reaction Steps
Proceeding as in Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2-(2-ethyloxyphenoxy)ethyl methanesulfonate and [2-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2-(1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(1H-indol-3-yl)-1,1-dimethylethyl][2-(2-ethyloxy-phenoxy)ethyl]amine hydrochloride, m.p. 184°-186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05436264 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-10990cfc08cb465c8b9137d67f93de25 |
| Source note | uspto-grants-1995_07 |