HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine → [2-(2-methylsulfonyl-1H-indol-3-yl)-1,1-dimethylethyl]{2-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-alpha,alpha-dimethyl-1H-indole-3-ethanamine | HCID 13260 | — |
| Reactant | 2-[2-(2-Methylprop-1-yloxy)phenoxy]ethyl methanesulfonate | HCID 15289997 | — |
| Reactant | [2-(2-methylsulfonyl-1H-indol-3-yl)-1,1-dimethylethyl]amine | HCID 19919941 | — |
| Product | [2-(2-methylsulfonyl-1H-indol-3-yl)-1,1-dimethylethyl]{2-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride | HCID 19919913 | — |
Reaction Steps
Proceeding as an Example 3, but replacing 2-[2-(cyclopropylmethyloxy)phenoxy]ethyl methanesulfonate with 2-[2-(2-methylprop-1-yloxy)phenoxy]ethyl methanesulfonate and [2-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine with [2-(2-methylsulfonyl-1H-indol-3-yl)-1,1-dimethylethyl]amine, gave [2-(2-methylsulfonyl -1H-indol-3-yl)-1,1-dimethylethyl]{2-[2-(2-methylprop-1-yloxy)phenoxy]ethyl}amine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05436264 |
| Source dataset | uspto-grants-1995_07 |
| ORD ID | ord-cdd6050115d7493d94fd2350b8107f26 |
| Source note | uspto-grants-1995_07 |