反应详情

A suspension of 15 g. finely powdered 4-nitrobenzoyl-β-alanine in 200 ml. ethanol was stirred in an atmosphere of hydrogen in the presence of 1 g. of palladium-charcoal (5%), while cooling gently. When the absorption of hydrogen had ceased, the reaction mixture was filtered and the filtrate concentrated to a small volume. Upon adding diethyl ether and cooling, 4-aminobenzoyl-β-alanine was obtained. The yield was 11.5 g.; m.p. 156°-158° C.

1. additionA suspension of 15 g
2. customWhen the absorption of hydrogen
3. filtrationthe reaction mixture was filtered
4. concentrationthe filtrate concentrated to a small volume
5. additionUpon adding diethyl ether
6. temperaturecooling