HCID 20481697, compound → HCID 20481689, compound

Participants

Reaction Steps

Ethyl 2-(3'-hydroxy-3'-methyl-4'-cyclohexyl-n-butyl)amino-9-tetrahydropyranyloxy-non-7-ynoate (7 g) was hydrogenated over 10% Pd/C (1.4 g) in dry dimethoxyethane (100 ml) at atmospheric pressure and room temperature. When hydrogen absorption was completed, the mixture was filtered through Kieselguhr, and the filtrate was evaporated in vacuo to give ethyl 2-(3'-hydroxy-3'-methyl-4'-cyclohexyl-n-butyl)amino-9-tetrahydropyranyloxy-nonanoate (7 g) as a pale yellow oil.

Provenance & Evidence