Pyridine → HCID 20154087, compound

HRID 1648742Notes

Reaction equation

HRID 1648742 reaction equation
[C:1]12([CH2:11][C:12]([C:14]3[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][CH:15]=3)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[Cl:21][C:22]1[CH:34]=[CH:33][C:25]([O:26][C:27]([CH3:32])([CH3:31])[C:28](Cl)=[O:29])=[CH:24][CH:23]=1.N1C=CC=CC=1>O>[C:1]12([CH2:11][C:12]([C:14]3[CH:15]=[CH:16][C:17]([O:20][C:28](=[O:29])[C:27]([O:26][C:25]4[CH:33]=[CH:34][C:22]([Cl:21])=[CH:23][CH:24]=4)([CH3:32])[CH3:31])=[CH:18][CH:19]=3)=[O:13])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Participants

5

Reactant 3

HCID 1049PyridineHCID 27813122-(4-Chlorophenoxy)-2-methylpropanoyl chlorideHCID 14202249HCID 14202249, compound

Product 1

HCID 20154087HCID 20154087, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

6.75 g (25 mmol) of p-(1-adamantylacetyl)-phenol and 6 g (25.7 mmol) of 2-(p-chlorophenoxy)-isobutyric acid chloride was mixed with 60 ml of dry pyridine and kept at 40° C. for 4 hours. After addition of 40 ml of water a crystalline product was obtained which was sucked off, washed with water and dried.

Workup

  1. customwas obtained which
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-9ac719c97fe44bf09e118531b4e4c214
Source dataset
uspto-grants-1983_11
Patent number
US04412998

Reaction notes

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