反应详情

温度

40 °C

42,4 g (200 mmol) of p-cumylphenol and 40 g (220 mmol) nicotinic acid chloride hydrochloride was mixed with 600 ml dry pyridine and stirred for 24 hours at 40° C. After cooling precipitated pyridine hydrochloride was sucked off and the filtrate mixed with 150 ml of water. The precipitated raw product was washed with two 100 ml portions of water and recrystallized from methanol.

1. temperatureAfter cooling
2. customprecipitated pyridine hydrochloride
3. additionthe filtrate mixed with 150 ml of water
4. customThe precipitated raw product
5. washwas washed with two 100 ml portions of water
6. customrecrystallized from methanol