HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isocyanate → N-(Ethylcarbamoyl)-N-[(ethylcarbamoyl)oxy]propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isocyanate | HCID 8022 | — |
| Reactant | Propionohydroxamic acid | HCID 75743 | — |
| Catalyst | Triethylamine | HCID 8471 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(Ethylcarbamoyl)-N-[(ethylcarbamoyl)oxy]propanamide | HCID 13228807 | — |
Reaction Steps
Propiohydroxamic acid (4.5 grams), ethyl isocyanate (8.0 grams), and a few drops of triethylamine were added to 100 ml of methylene chloride and allowed to stand at room temperature for about 12 hours. The solvent was then removed under vacuum leaving a residue which was recrystallized from a solution of methylene chloride and hexane leaving the desired, N-((ethylamino)carbonyl)-N-(((ethylamino)carbonyl)oxy)propionamide as white crystals, m.p. 104°-106° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04413009 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-927f6c10ae484f9babd8e38cfc30aa76 |
| Source note | uspto-grants-1983_11 |