Boron trifluoride etherate → HCID 12909378, compound

Participants

Reaction Steps

Racemic 5-(1-methyl-4-piperidylidene)-5H-dibenzo[a,d]cycloheptene-3-carboxylic acid (0.03 mole) and an equal molar amount of boron trifluoride etherate in 60 ml of absolute ethanol was refluxed overnight. The solution was evaporated to dryness and the residue was partitioned between ether and a saturated aqueous solution of sodium bicarbonate. The ether was separated and dried over MgSO4. The resulting ethyl ester, crystallized from acetonitrile, had m.p. 102°-103° C.

Provenance & Evidence