HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 4-Ethoxy-3-(4-pyridyl)-3-buten-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 4-Pyridinylacetone | HCID 80552 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-Ethoxy-3-(4-pyridyl)-3-buten-2-one | HCID 3021227 | — |
Reaction Steps
The process according to claim 2 where 4-pyridinylmethyl methyl ketone is first reacted with triethyl orthoformate, acetic anhydride and acetic acid to produce 2-ethoxy-1-(4-pyridinyl)ethenyl methyl ketone and then refluxing said ketone with malononitrile in ethanol to produce 1,2-dihydro-6-methyl-2-oxo-5-(4-pyridinyl)nicotinonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04413127 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-8e1952493aa04207bd9b331d09e8129d |
| Source note | uspto-grants-1983_11 |