HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Milrinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | 4-Ethoxy-3-(4-pyridyl)-3-buten-2-one | HCID 3021227 | — |
| Product | Milrinone | HCID 4197 | — |
Reaction Steps
The process according to claim 4 where 2-ethoxy-1-(4-pyridinyl)ethenyl methyl ketone is refluxed with malononitrile in ethanol to produce 1,2-dihydro-6-methyl-2-oxo-5-(4-pyridinyl)nicotinonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04413127 |
| Source dataset | uspto-grants-1983_11 |
| ORD ID | ord-ee06fb388521427aa7b39ed778f27469 |
| Source note | uspto-grants-1983_11 |