Thiosulfuric acid (H2S2O3), S-(2-aminoethyl) ester → HCID 178433288, compound

HRID 1648815Notes

Reaction equation

HRID 1648815 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[CH2:7]O.[CH2:9]([NH2:16])[CH2:10][S:11]S(O)(=O)=O>>[CH3:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[CH2:7][S:11][CH2:10][CH2:9][NH2:16]

Participants

3

Reactant 2

HCID 76242Thiosulfuric acid (H2S2O3), S-(2-aminoethyl) esterHCID 178433277HCID 178433277, compound

Product 1

HCID 178433288HCID 178433288, compoundYield 70.1%

Procedure

In the same manner as in Example 1 (i), 2.8 g of 4-methyl-5-hydroxymethylimidazole (free base) is reacted with 4.3 g of 2-aminoethanethiolsulfuric acid, yielding 3.0 g of 4-methyl-5-[(2-aminoethyl)thiomethyl]imidazole as an oily product (yield: 72.0%).

Sources & evidence

ORD record
ord-dcde724e87254a8997588d1273500648
Source dataset
uspto-grants-1983_11
Patent number
US04413129

Reaction notes

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