Thiosulfuric acid (H2S2O3), S-(2-aminoethyl) ester → HCID 178433288, compound

HRID 1648816Notes

Reaction equation

HRID 1648816 reaction equation
S(O)(O)(=O)=O.[CH3:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[CH2:12]O.[CH2:14]([NH2:21])[CH2:15][S:16]S(O)(=O)=O>>[CH3:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[CH2:12][S:16][CH2:15][CH2:14][NH2:21]

Participants

3

Reactant 2

HCID 76242Thiosulfuric acid (H2S2O3), S-(2-aminoethyl) esterHCID 178433282HCID 178433282, compound

Product 1

HCID 178433288HCID 178433288, compoundYield 97.2%

Procedure

4.8 g of 4-methyl-5-hydroxymethylimidazole sulfate is reacted with 5.2 g of 2-aminoethanethiolsulfuric acid according to the procedure described in Example 1 (i), yielding 3.8 g of 4-methyl-5-[(2-aminoethyl)thiomethyl]imidazole as an oily product (yield: 73.3%).

Sources & evidence

ORD record
ord-612e66f8461b46ce8d03bdad79a69b23
Source dataset
uspto-grants-1983_11
Patent number
US04413129

Reaction notes

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