Ethyl 6-benzyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine-2-carboxylate → HCID 13072040, compound

HRID 1648935Notes

Reaction equation

HRID 1648935 reaction equation
[CH2:1]([N:8]1[CH2:14][CH2:13][C:12]2[CH:15]=[C:16]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[S:17][C:11]=2[CH2:10][CH2:9]1)[C:2]1C=CC=CC=1>[Ni].C(O)C>[CH2:1]([N:8]1[CH2:14][CH2:13][C:12]2[CH:15]=[C:16]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[S:17][C:11]=2[CH2:10][CH2:9]1)[CH3:2]

Participants

4

Reactant 1

HCID 13072038Ethyl 6-benzyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine-2-carboxylate

Product 1

HCID 13072040HCID 13072040, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

3.15 gm (0.01 mol) of ethyl 6-benzyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine-2-carboxylate were refluxed with the same amount of Raney nickel in 50 ml of ethyl alcohol for 6 hours. The catalyst was then removed by suction filtering, and the filtrate was concentrated by evaporation.

Workup

  1. customThe catalyst was then removed by suction
  2. filtrationfiltering
  3. concentrationthe filtrate was concentrated by evaporation

Sources & evidence

ORD record
ord-024c7012f65d4a58a5092da722aa51a2
Source dataset
uspto-grants-1983_11
Patent number
US04414225

Reaction notes

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