1-Bromomethyl-2,6-dichlorobenzene → 6-(2,6-Dichlorobenzyl)-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine hydrochloride

HRID 1648939Notes

Reaction equation

HRID 1648939 reaction equation
[S:1]1[C:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10][C:4]=2[CH:3]=[CH:2]1.[Cl:11][C:12]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[C:13]=1[CH2:14]Br>>[ClH:11].[Cl:11][C:12]1[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[C:13]=1[CH2:14][N:8]1[CH2:9][CH2:10][C:4]2[CH:3]=[CH:2][S:1][C:5]=2[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 301591-Bromomethyl-2,6-dichlorobenzeneHCID 115137774H,5H,6H,7H,8H-thieno[2,3-d]azepine

Product 1

HCID 204813136-(2,6-Dichlorobenzyl)-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine hydrochloride

Procedure

This compound was prepared analogous to Example 17 from 5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine and 2,6-dichlorobenzyl bromide.

Sources & evidence

ORD record
ord-eb16a6d1a2a94c469ba000f3785704d5
Source dataset
uspto-grants-1983_11
Patent number
US04414225

Reaction notes

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