Benzyl Alcohol → HCID 20284004, compound

HRID 1648962Notes

Reaction equation

HRID 1648962 reaction equation
[CH2:1]([OH:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:9]([N:15]=[C:16]=[O:17])([N:12]=[C:13]=[O:14])(=[O:11])=[O:10]>C1C=CC=CC=1>[CH2:1]([O:8][C:13]([NH:12][S:9]([NH:15][C:16]([O:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:17])(=[O:11])=[O:10])=[O:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 244Benzyl AlcoholHCID 77898Sulphonyl diisocyanate

Product 1

HCID 20284004HCID 20284004, compoundYield 107.2%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

10 g of anhydrous benzyl alcohol are placed in 150 ml of absolute benzene and 7.4 g of sulfuryl diisocyanate are added dropwise accompanied by stirring. The exothermic reaction which takes place leads to a rise in the temperature to 45° C. and shortly after the start a precipitate is formed. Following the temperature drop, stirring is continued for 1 hour at ambient temperature. The resulting precipitate is suction filtered and dried at 60° C. giving a yield of 18.06 g of colorless crystals (99.2% of theory), m.p. 139°-141° C., which can be recrystallized from ethanol.

Workup

  1. customThe exothermic reaction which
  2. customleads to a rise in the temperature to 45° C.
  3. customshortly after the start a precipitate is formed
  4. stirringstirring
  5. filtrationfiltered
  6. customdried at 60° C.

Sources & evidence

ORD record
ord-db3fe2899a2f4b80a5871ef432251b25
Source dataset
uspto-grants-1983_11
Patent number
US04414347

Reaction notes

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