6-Nitro-2-oxo-1,2,3,4-tetrahydroquinolin-8-yl acetate → 8-Hydroxy-6-nitro-3,4-dihydroquinolin-2(1H)-one

Participants

Reaction Steps

Hydrochloric acid (200 ml) was added to 6-nitro-8-acetoxy-3,4-dihydrocarbostyril (20 g) and the mixture was refluxed for 4 hours. After ice cooling, crystals which precipitated were collected by filtration and recrystallized from methanol to give 13.76 g of 6-nitro-8-hydroxy-3,4-dihydrocarbostyril.

Provenance & Evidence